The synthesis of IFN-β during genital tract Chlamydia muridarum infection is important in minimizing the genital tract pathology caused by the immune responses to chlamydial infection

Chlamydia trachomatis (Ct) is the most common bacterial sexually transmitted pathogen and is a significant threat to the reproductive health of women. With an estimated 2.8 million new infections domestically and 131 million new Ct infections acquired annually globally, chlamydia is costing health care systems billions of dollars to treat not only the acute infections but also the complications they cause. Ct genital tract infections are associated with cervicitis, urethritis, and endometritis; complications from chronic infections include pelvic inflammatory disease (PID) and its sequelae of chronic pelvic pain, ectopic pregnancy, and tubal infertility. Although treatable with antibiotics, individuals infected with Ct are often unaware of the infection, and the asymptomatic nature of the disease facilitates the spread of the bacterium through further sexual contact with uninfected individuals. As a result, Ct infections have continued to increase over the past two decades, despite the implementation of screening and early intervention strategies.

Creator

• Nick, Benjamin
• Donner, Faith
• Kumar, Ramesh
• Derbigny, Wilbert

Language

• English

Palabra Clave

• Chlamydia muridarum
• infection
• IFN-β
• Chlamydia trachomatis

Date created

• 2021

Related URL

• Audio Presentation:  https://marian.hosted.panopto.com/Panopto/Pages/Viewer.aspx?id=15da2550-5bf1-4cdc-8bd1-adf7011ba56a

Resource type

• Poster

Rights statement

• http://rightsstatements.org/vocab/InC/1.0/