Characterization of Spatio-Temporal Expression of Novel Hypoxia-Induced Genes in Zebrafish

Hypoxia is a critical stress that can affect the normal development of a mammal embryo. Normally, Hypoxia is buffered by the Utero-placental apparatus in human infants; however, prematurely delivered infants may encounter developmental defects due to the loss of the controlled environment of the uterus. Therefore, understanding the function of the genes that are hypoxia-induced is critical to understanding developmental injury in order to attempt to prevent or treat it. Why zebrafish as a model? Experimenting with zebrafish has many advantages: Approximately 2/3 of its genome is conserved with Humans, Zebrafish embryos can tolerate a wide range of hypoxia and the embryos develop ex-utero, which allows precise manipulation of the hypoxic environment and observation of phenotypes.

Creator

• Amir, Adam
• Imam, Farhad

Language

• English

Palavra-chave

• mammal embryo development
• Hypoxia
• zebrafish
• observation of phenotypes

Date created

• 1/1/2015

Resource type

• poster

Source

• mucom_rd_7

Rights statement

• http://rightsstatements.org/vocab/InC/1.0/