Assessment of bone healing agents for promoting bone regeneration in spaceflight

Segmental bone defects secondary lo high-energy trauma may not spontaneousfy heal and orthopedic surgeons call on the use of bone graft substitutes. Bone morphogenetic prntein-2 (BMP-2) and thrombopoietin (TPO) are an FDA approved and a novel therapeutic alternative, respectively, lo revitalize these bone grafts thus stimulating osteogenesis. With the growing global interest in space exploration and colonization, these drugs may be used in the absence of loading conditions, which may interfere with their mechanisms and actions.

Creator

• Dadwal, U
• Zamarioli, Ariane
• Childress, P
• Campbell, Zachery
• Kacena, M

Language

• English

Mot-clé

• bone regeneration
• spaceflight
• thrombopoietin (TPO)
• Bone morphogenetic protein-2 (BMP-2)

Date created

• 2020

Related URL

• Video presentation here:  https://marian.hosted.panopto.com/Panopto/Pages/Viewer.aspx?id=221ddfad-5ade-4135-afac-ac74003017cb

Resource type

• Poster

Rights statement

• http://rightsstatements.org/vocab/InC/1.0/