- Coincidencias de palabras clave:
... The FASEB Journal Research Communication SDF-1/CXCL12 induces directional cell migration and ...
... . Molinolo,* and J. Silvio Gutkind*,1 *Oral and Pharyngeal Cancer Branch, National Institute of Dental and ...
... (CXCR4) and its ligand, SDF-1/CXCL12 (stroma cellderived factor 1/C-X-C motif chemokine 12), to ...
... . Inhibition of mTOR complex 1 (mTORC1) by rapamycin [drug concentration causing 50% inhibition (IC50) = 5 nM ...
... rapamycin. In contrast, disrupting mTORC2 had no effect in tumor growth or metastasis compared with control ...
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- Creador:
- Mikelis, Constantinos M., Zárate-Bladés, Carlos Rodrigo, Leelahavanichkul, Kantima, Wang, Zhiyong, Martin, Daniel, Doci, Colleen L., Dorsam, Robert T., Amornphimoltham, Panomwat, Gutkind, J. Silvio, Patel, Vyomesh, Weigert, Roberto, Masedunskas, Andrius, Molinolo, Alfredo A., and Dillenburg-Pilla, Patricia
- Descripción:
- Multiple human malignancies rely on C-X-C motif chemokine receptor type 4 (CXCR4) and its ligand, SDF-1/CXCL12 (stroma cell-derived factor 1/C-X-C motif chemokine 12), to metastasize. CXCR4 inhibitors promote the mobilization...
- Tipo de recurso:
- Article