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  • The Transcriptional Co-Repressor TLE3 Regulates Myogenic Differentiation by Repressing the Activity of the MyoD Transcription Factor

    Coincidencias de palabras clave:
    ... revised form, June 8, 2017 Published, Papers in Press, June 12, 2017, DOI 10.1074/jbc.M116.774570 Edited ...
    ... Rosen and Eijiro Jimi J. Biol. Chem. 2017, 292:12885-12894. doi: 10.1074/jbc.M116.774570 originally ...
    ... : 10.1074/jbc.M116.774570 ...
    Creador:
    Addison, William N, Yoda, Tetsuya, Rosen, Vicki, Nakatomi, Mitsushiro, Nakatomi, Chihiro, Urata, Mariko, Hitomi, Suzuro, Osawa, Kenji;, Jimi, Eijiro, Sato, Tsuyoshi, Ono, Yusuke, Kokabu, Shoichiro, Matsubara, Takuma, Hudnall, Aaron M, and Lowery, Jonathan W.
    Descripción:
    Satellite cells are skeletal muscle stem cells that provide myonuclei for postnatal muscle growth, maintenance, and repair/regeneration in adults. Normally, satellite cells are mitotically quiescent, but they are activated in...
    Tipo de recurso:
    Article

  • Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis.

    Coincidencias de palabras clave:
    ... . J Biol Chem 288, 1223212243, https://doi.org/10.1074/jbc.M112.428599 (2013). 21. Zeng, H., Zhao, D ...
    ... activation of a small GTPase RhoA. J Biol Chem 277, 4679146798, https://doi.org/10.1074/jbc.M206133200 (2002 ...
    ... mitosis in primary mouse embryonic fibroblasts. J Biol Chem 286, 1513215137, https://doi.org/10.1074 ...
    ... function coordinately during embryonic angiogenesis. J Biol Chem 279, 2936729373, https://doi.org/10.1074 ...
    ... . J Biol Chem 277, 2515225159, https://doi.org/10.1074/jbc. M200137200 (2002). 50. Ishii, I. et al ...
    Creador:
    Tuz Zahra, Fatema, Kubota, Yoshiaki, Doci, Colleen L., Minchew, Shelby A., Cobos, Christopher, Gutkind, J. Silvio, Mikelis, Constantinos M., Zheng, Yi, Ichiyama, Yusuke, Sajib, Sanaullah, Tullar, Paul E., and Akwii, Racheal Grace
    Descripción:
    Imbalanced angiogenesis is a characteristic of several diseases. Rho GTPases regulate multiple cellular processes, such as cytoskeletal rearrangement, cell movement, microtubule dynamics, signal transduction and gene...
    Tipo de recurso:
    Article

  • Regulation of macrophage IFNγ-stimulated gene expression by the transcriptional coregulator CITED1

    Coincidencias de palabras clave:
    ... -activator for transcription factor AP-2. J. Biol. Chem. 277, 8559-8565. doi:10.1074/jbc.M110850200 ...
    ... 1 gene expression. J. Biol. Chem. 273, 16177-16183. doi:10.1074/jbc.273.26. 16177 13 Journal of Cell ...
    ... cell leukemia/lymphoma 6 expression. J. Biol. Chem. 291, 21271-21282. doi:10.1074/jbc.M116.738617 Kim ...
    ... transcription of the gp91( phox) gene. J. Biol. Chem. 277, 9103-9111. doi:10.1074/jbc.M109803200 Langlais, D ...
    ... -27435. doi:10.1074/jbc.M602631200 Shioda, T., Fenner, M. H. and Isselbacher, K. J. (1996). msg1, a novel ...
    Creador:
    Subramani, A., Hite, M., Garcia, S., Maxwell, J., Kondee, H., Millican, G., McClelland, Erin E., Seipelt-Thiemann, R., and Nelson, D.
    Descripción:
    Macrophages serve as a first line of defense against microbial pathogens. Exposure to interferon-γ (IFNγ) increases interferon-stimulated gene (ISG) expression in these cells, resulting in enhanced antimicrobial and...
    Tipo de recurso:
    Article

  • Clinical Relevance and Mechanisms of Antagonism Between the BMP and Activin/TGF-? Signaling Pathways.

    Coincidencias de palabras clave:
    ... pathways. J Biol Chem. 2012;287(34):29101-29113. doi:10.1074/jbc.M112.349415. 25. Hanada K, Solchaga LA ...
    ... ) production. Mol Cell Proteomics. 2013;12(10):2890-2900. doi:10.1074/mcp.M112.024927. 32. von Haehling S ...
    ... . doi:10.1074/jbc.M109.077347. The Journal of the American Osteopathic Association July 2016 | Vol 116 ...
    Creador:
    Arthur JW, Hudnall, AM, and Lowery, Jonathan W.
    Descripción:
    The transforming growth factor ? (TGF-?) superfamily is a large group of signaling molecules that participate in embryogenesis, organogenesis, and tissue homeostasis. These molecules are present in all animal genomes....
    Tipo de recurso:
    Article

  • Dysfunctional Stem and Progenitor Cells Impair Fracture Healing with Age

    Coincidencias de palabras clave:
    ... mesenchymal stem cells. J Biol Chem 2014; 289: 22048-22062 [PMID: 24962570 DOI: 10.1074/jbc.M114.568790] Lu C ...
    ... DOI: 10.1074/jbc.271.45.28266] Gissln M, Hagberg L, Norkrans G, Lekman A, Fredman P. Increased ...
    ... Biol Chem 2014; 289: 10330-10344 [PMID: 24550383 DOI: 10.1074/jbc.M113.546382] Costa V, Carina V ...
    Creador:
    Kacena, M.A., Karnik, S., Li, J., Promer, H.J., Clauss, M., Loghmani, M.T., Wagner, D.R., McKinley, T.O., Nielsen, J.J., Low, P.S., Lowery, Jonathan W., Gunderson, Z.J., and Fennimore, A.
    Descripción:
    Successful fracture healing requires the simultaneous regeneration of both the bone and vasculature; mesenchymal stem cells (MSCs) are directed to replace the bone tissue, while endothelial progenitor cells (EPCs) form the new...
    Tipo de recurso:
    Article

  • Abnormal Trafficking of Endogenously Expressed BMPR2 Mutant Allelic Products in Patients with Heritable Pulmonary Arterial Hypertension

    Coincidencias de palabras clave:
    ... sodium 4-phenylbutyrate in human nasal epithelial cells. J Biol Chem 282: 34048-34057. doi:10.1074 ...
    Creador:
    Frump, A.L., Hamid, R., de Caestecker, M., Austin, E.D., and Lowery, Jonathan W.
    Descripción:
    More than 200 heterozygous mutations in the type 2 BMP receptor gene, BMPR2, have been identified in patients with Heritable Pulmonary Arterial Hypertension (HPAH). More severe clinical outcomes occur in patients with BMPR2...
    Tipo de recurso:
    Article