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  • Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis.

    Creador:
    Tuz Zahra, Fatema, Kubota, Yoshiaki, Doci, Colleen L., Minchew, Shelby A., Cobos, Christopher, Gutkind, J. Silvio, Mikelis, Constantinos M., Zheng, Yi, Ichiyama, Yusuke, Sajib, Sanaullah, Tullar, Paul E., and Akwii, Racheal Grace
    Descripción:
    Imbalanced angiogenesis is a characteristic of several diseases. Rho GTPases regulate multiple cellular processes, such as cytoskeletal rearrangement, cell movement, microtubule dynamics, signal transduction and gene...
    Tipo de recurso:
    Article

  • Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer.

    Creador:
    Doci, Colleen L., Gutkind, J. Silvio, and Sakurai, Atsuko
    Descripción:
    Angiogenesis, the formation of new blood vessels from preexisting vasculature, is essential for many physiological processes, and aberrant angiogenesis contributes to some of the most prevalent human diseases, including cancer....
    Tipo de recurso:
    Article

  • The novel tumor suppressor NOL7 post-transcriptionally regulates thrombospondin-1 expression.

    Creador:
    Zhou, G., Doci, Colleen L., and Lingen, M.W.
    Descripción:
    Thrombospondin-1 (TSP-1) is an endogenous inhibitor of angiogenesis whose expression suppresses tumor growth in vivo. Like many angiogenesis-related genes, TSP-1 expression is tightly controlled by various mechanisms, but there...
    Tipo de recurso:
    Article