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  • Bone-derived Sclerostin has endocrine actions in adipocyte precursors and pancreatic beta-cells

    Creador:
    Nelson, Jessica, Ghazzawi, Ziad, Evans-Molina, Carmela, Thompson, William, Cregor, Meloney, Bellido, Teresita, Daniel, Ashley, Delgado-Calle, Jesus, Ferrari, Adam, Sabol, Hayley, and McAndrews, Kevin
    Descripción:
    Osteocyte (Ot)-derived Sclerostin (Scl) has local actions in bone mediated by Lrp 4/5/6 receptors, inhibiting bone formation and stimulating bone resorption by antagonizing Wnt signaling. Emerging evidence suggests that Scl...
    Tipo de recurso:
    poster

  • Bone-derived Sclerostin Regulates Glucose Metabolism Via Endocrine Actions in Pancreatic β- cells

    Creador:
    Nelson, Jessica, Evans-Molina, Carmella, Cregor, Meloney, Bellido, Teresita, Delgado-Calle, Jesus, Ferrari, Adam, and McAndrews, Kevin
    Descripción:
    Osteocyte (Ot)-derived Sclerostin (Scl), encoded by the SOST gene, regulates bone homeostasis by acting on osteoblasts, inhibiting bone formation and stimulating bone resorption. Emerging evidence suggest that Scl has...
    Tipo de recurso:
    poster