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新搜索 Identifier Tesim 10.1371/journal.pone.0173692

  • Epidermal Loss of Gag Confers a Migratory and Differentiation Defect in Keratinocytes

    关键字匹配:
    ... pathologic conditions. PLOS ONE | https://doi.org/10.1371/journal.pone.0173692 March 16, 2017 1 / 18 ...
    ... mice used were in C57BL/6 PLOS ONE | https://doi.org/10.1371/journal.pone.0173692 March 16, 2017 2 / 18 ...
    ... /journal.pone.0173692.t001 PLOS ONE | https://doi.org/10.1371/journal.pone.0173692 March 16, 2017 3 / 18 ...
    ... Axio PLOS ONE | https://doi.org/10.1371/journal.pone.0173692 March 16, 2017 4 / 18 Epidermal loss of ...
    ... (Ki67), and differentiation (K10). https://doi.org/10.1371/journal.pone.0173692.g001 PLOS ONE | https ...
    创造者:
    Mikelis, Constantinos M., Gutkind, J. Slivio , Molinolo, Alfredo A. , Inoue, Asuka , Callejas-Valera, Juan Luis , Doci, Colleen L., Hansen, Karina K. , and Offermanns, Stefan
    描述:
    G-protein coupled receptors (GPCRs), which activate heterotrimeric G proteins, are an essential class of transmembrane receptors that are responsible for a myriad of signaling events in normal and pathologic conditions. Two...
    类型:
    Article

  • Building an Epigenetic Database: Reproducibility and Orthogonal Targets

    关键字匹配:
    ... 10.3892/etm.2012.710 0.87 10.1016/j.nut.2016.05.009 2.10 10.1111/jgh.12805 10.1371/journal.pone.01932 1.71 ...
    ... 32 10.1371/journal.pone.01932 2.59 32 10.1371/journal.pone.01932 1.16 32 10.3349/ymj.2015.56.6.166 ...
    ... 1.46 3 10.1038/s41598-017-04206 1.17 -6 10.1371/journal.pone.01932 1.33 32 10.1371/journal.pone.01932 ...
    ... 1.16 32 10.1371/journal.pone.01932 1.79 32 10.1371/journal.pone.01932 1.53 32 1 yes/no 1 binary (1/0 ...
    ... ) 10.1371/journal.pone.01932 3.04 32 1 yes/no 1 binary (1/0) 10.1371/journal.pone.01932 5.33 32 1 yes/no 1 ...
    创造者:
    Arbor, Sage, Given, Scott, Zhang, Eric, and Dryden, Ariel
    描述:
    Odds ratios are one of the methods in statistics to quantify how strongly the presence or absence of a property correlates with the presence or absence of another property in a given population. In the biomedical sciences they...
    类型:
    poster

  • Comparative Genomics Identifies the Mouse BMP3 Promoter and an Upstream Evolutionary Conserved Region (ECR) in Mammals.

    关键字匹配:
    ... Region (ECR) in Mammals. PLoS ONE 8(2): e57840. doi:10.1371/journal.pone.0057840 Editor: Bernd Sokolowski ...
    ... indicates 59-end of Bmp3 exon 1 in M. musculus. doi:10.1371/journal.pone.0057840.g001 and R. norvegicus ...
    ... 20.800 kb fragment. doi:10.1371/journal.pone.0057840.g002 To determine the function of the Bmp3 CoreECR ...
    ... . norvegicus, H. sapiens, and B. taurus are based upon the primary assembly. doi:10.1371/journal.pone.0057840 ...
    ... control and by b versus 20.800 kb fragment. doi:10.1371/journal.pone.0057840.g004 (ESTs), which comprise ...
    创造者:
    LaVigne, AW, Kokabu, S, Lowery, Jonathan W., and Rosen, V.
    描述:
    The Bone Morphogenetic Protein (BMP) pathway is a multi-member signaling cascade whose basic components are found in all animals. One member, BMP3, which arose more recently in evolution and is found only in deuterostomes,...
    类型:
    Article

  • Abnormal Trafficking of Endogenously Expressed BMPR2 Mutant Allelic Products in Patients with Heritable Pulmonary Arterial Hypertension

    关键字匹配:
    ... :10.1371/journal.pone.0080319 Editor: Philip Michael Bauer, University of Pittsburgh School of Medicine ...
    ... : 10.1371/journal.pone.0080319.g001 PLOS ONE | www.plosone.org 4 November 2013 | Volume 8 | Issue 11 ...
    ... ). doi: 10.1371/journal.pone.0080319.g003 the endoplasmic reticulum (ER) and Golgi apparatus. N-linked ...
    ... additional chemical chaperone, TUDCA doi: 10.1371/journal.pone.0080319.g002 cultured lymphocytes, the 130 kDa ...
    ... controls from three independent experiments. doi: 10.1371/journal.pone.0080319.g004 BMP signaling defects ...
    创造者:
    Frump, A.L., Hamid, R., de Caestecker, M., Austin, E.D., and Lowery, Jonathan W.
    描述:
    More than 200 heterozygous mutations in the type 2 BMP receptor gene, BMPR2, have been identified in patients with Heritable Pulmonary Arterial Hypertension (HPAH). More severe clinical outcomes occur in patients with BMPR2...
    类型:
    Article

  • PrEP Provision and Persistence among Primary Care Providers

    关键字匹配:
    ... -exposure prophylaxis and associated care. PLoS One, 11(6). https://doi.org/10.1371/journal.pone.0157324 ...
    ... ): e0223486. https://doi.org/10.1371/journal.pone.0223486 Leech, A. A., Christiansen, C. L., Linas, B. P ...
    ... United States, 2015-2016. PLoS Medicine, 17(4): e1003072. https://doi.org/10.1371/journal.pmed.1003072 ...
    ... to prescribe pre-exposure prophylaxis in the US. PLoS ONE, 15(9): e0238375. https://doi.org/10.1371 ...
    ... /journal.pone.0238375 Logo, M. K., Danawi, H., & Ferraro, A. (2017). Prescribing HIV PrEP and education needs ...
    创造者:
    Holder, Chauna
    描述:
    <b>Background and Review of Literature</b>: This study examined individual opinions from healthcare providers in Indiana about their willingness to prescribe Pre-Exposure Prophylaxis (PrEP) for Human Immunodeficiency Virus...
    类型:
    Research Paper

  • The lipidomes of C. elegans with mutations in asm-3/acid sphingomyelinase and hyl-2/ceramide synthase show distinct lipid profiles during aging

    关键字匹配:
    ... using shotgun lipidomics. PLoS One. 2011; 6:e21643. https://doi.org/10.1371/journal.pone.0021643 PMID ...
    ... One. 2009; 4:e6261. https://doi.org/10.1371/journal.pone.0006261 PMID:19603071 www.aging-us.com 13 ...
    ... . 2012; 7:e45890. https://doi.org/10.1371/journal.pone.0045890 PMID:23049887 16. Kounakis K, Chaniotakis ...
    ... lifespan extension in C. elegans. PLoS One. 2013; 8:e70087. https://doi.org/10.1371/journal.pone.0070087 ...
    ... . 2009; 4:e7545. https://doi.org/10.1371/journal.pone.0007545 PMID:19844570 37. Prasain JK, Wilson L ...
    创造者:
    Staab, Trisha, McIntyre, Grace, Bromley, S., Raftery, D., Chan, Jason, Wang, L., Radeny, J., Bettcher, L., Guillen, Melissa, Peck, M. , and Kalil, A.
    描述:
    Lipid metabolism affects cell and physiological functions that mediate animal healthspan and lifespan. Lipidomics approaches in model organisms have allowed us to better understand changes in lipid composition related to age...
    类型:
    Research Paper

  • Temporal Transcriptomics of Gut Escherichia coli in Caenorhabditis elegans Models of Aging

    关键字匹配:
    ... :e60731. https://doi.org/10.1371/journal.pone.0060731. 40. Back P, De Vos WH, Depuydt GG, Matthijssens F ...
    ... -aging target. PLoS One 7:e45890. https://doi.org/10.1371/journal .pone.0045890. Portal-Celhay C, Bradley ...
    ... lifespan. PLoS Biol 8:e1000376. https://doi.org/10.1371/ journal.pbio.1000376. 50. Troemel ER, Chu SW ...
    ... contributes to longevity in C. elegans. PLoS Genet 2:e183. https://doi.org/10.1371/ journal.pgen.0020183. 51 ...
    ... Caenorhabditis elegans. PLoS Genet 7: e1002082. https://doi.org/10.1371/journal.pgen.1002082. 52. Tanaka T ...
    创造者:
    Brycky, J, Brislawn, C, Chan, Jason, Heibeck, N, Letson, G, Buonaccorsi, V, Unverdorben, L, Emlet, C, Chen See, J, and Lamendella, R
    类型:
    Article

  • Dysfunctional Stem and Progenitor Cells Impair Fracture Healing with Age

    关键字匹配:
    ... : e0166590 [PMID: 27855196 DOI: 10.1371/journal.pone.0166590] Choudhery MS, Badowski M, Muise A, Pierce J ...
    ... regulation of RUNX2 by TWIST. PLoS One 2011; 6: e23965 [PMID: 21931630 DOI: 10.1371/journal.pone.0023965 ...
    ... : 23185479 DOI: 10.1371/journal.pone.0049896] Potier E, Ferreira E, Meunier A, Sedel L, Logeart-Avramoglou D ...
    ... therapeutic target for osteoporosis. PLoS One 2017; 12: e0185236 [PMID: 28937996 DOI: 10.1371/journal.pone ...
    ... trabecular bone during reambulation. PLoS One 2010; 5: e11178 [PMID: 20567514 DOI: 10.1371/journal.pone ...
    创造者:
    Kacena, M.A., Karnik, S., Li, J., Promer, H.J., Clauss, M., Loghmani, M.T., Wagner, D.R., McKinley, T.O., Nielsen, J.J., Low, P.S., Lowery, Jonathan W., Gunderson, Z.J., and Fennimore, A.
    描述:
    Successful fracture healing requires the simultaneous regeneration of both the bone and vasculature; mesenchymal stem cells (MSCs) are directed to replace the bone tissue, while endothelial progenitor cells (EPCs) form the new...
    类型:
    Article

  • Regulation of macrophage IFNγ-stimulated gene expression by the transcriptional coregulator CITED1

    关键字匹配:
    ... , e0145342. doi:10.1371/journal.pone.0145342 Kim, Y.-M., Lee, B.-S., Yi, K.-Y. and Paik, S.-G. (1997 ...
    ... -seq data. PLoS One 11, e0157022. doi:10.1371/journal.pone.0157022 Waltermann, A., Kartasheva, N. N ...
    ... vaccinia virus infection. PLoS Pathog. 13, e1006651. doi:10.1371/journal.ppat.1006651 Becton, D. L., Adams ...
    ... . 1371/journal.pone.0045466 Bhattacharya, S., Michels, C. L., Leung, M. K., Arany, Z. P., Kung, A. L. and ...
    ... the life sciences. PLoS Biol. 14, e1002342. doi:10.1371/journal.pbio.1002342 Michalska, A., Blaszczyk ...
    创造者:
    Subramani, A., Hite, M., Garcia, S., Maxwell, J., Kondee, H., Millican, G., McClelland, Erin E., Seipelt-Thiemann, R., and Nelson, D.
    描述:
    Macrophages serve as a first line of defense against microbial pathogens. Exposure to interferon-γ (IFNγ) increases interferon-stimulated gene (ISG) expression in these cells, resulting in enhanced antimicrobial and...
    类型:
    Article

  • A chromosome-scale genome sequence of sudangrass (Sorghum sudanense) highlights the genome evolution and regulation of dhurrin biosynthesis

    关键字匹配:
    ... alignments. PLoS ONE 5:e9490. https://doi.org/10.1371/journal.pone.0009490 41. Provin TL, Pitt JL, Texas A ...
    ... assembly improvement. PLoS ONE 9:e112963. https://doi.org/10.1371/journal.pone.0112963 51. Wang L ...
    创造者:
    Bible, Paul, W., Wang, L., Jin, P., Zheng, J., Wang, Y., Zhan, Q., Li, J., Liu, Y., and Tu, W.
    描述:
    Sudangrass [ Sorghum sudanense (Piper) Stapf] is a hybrid between grain sorghum and its wild relative S. bicolor ssp. verticilliflorum and is grown as a forage crop due to its high biomass production and low dhurrin content...
    类型:
    Article