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Nova pesquisa Identifier Tesim DOI: 10.1152/japplphysiol.00746.2021

  • Clinical Relevance and Mechanisms of Antagonism Between the BMP and Activin/TGF-? Signaling Pathways.

    Correspondências de palavras-chave:
    ... . J Appl Physiol (1985). 2010;109(3):635-642. doi:10.1152/japplphysiol.00866.2009. 34. Lee SJ, Reed LA ...
    ... Appl Physiol (1985). 2009;106(4):1356-1364. doi:10.1152/japplphysiol.90719.2008. 38. Bazan IS, Fares WH ...
    ... Lung Cell Mol Physiol. 2012;302(6):L604-L615. doi:10.1152/ajplung.00309.2011. The Journal of the ...
    ... Assoc. 2016;116(7):452-461 doi:10.7556/jaoa.2016.089 T he transforming growth factor (TGF-) superfamily ...
    ... receptors: insights into evolution of the TGF-s superfamily. FEBS Lett. 2012;586(14):1860-1870. doi:10.1016 ...
    O Criador:
    Arthur JW, Hudnall, AM, and Lowery, Jonathan W.
    Descrição:
    The transforming growth factor ? (TGF-?) superfamily is a large group of signaling molecules that participate in embryogenesis, organogenesis, and tissue homeostasis. These molecules are present in all animal genomes....
    Tipo:
    Article

  • Dysfunctional Stem and Progenitor Cells Impair Fracture Healing with Age

    Correspondências de palavras-chave:
    ... DOI: 10.1152/japplphysiol.01183.2006] Scheubel RJ, Zorn H, Silber RE, Kuss O, Morawietz H, Holtz J ...
    ... Heart Circ Physiol 2004; 287: H2651-H2658 [PMID: 15284068 DOI: 10.1152/ajpheart.00332.2004] Yoder MC ...
    ... 344 rats. Am J Physiol Heart Circ Physiol 2003; 285: H1015-H1022 [PMID: 12915388 DOI: 10.1152/ajpheart ...
    ... ; 286: H2249-H2256 [PMID: 14751861 DOI: 10.1152/ajpheart.00854.2003] Ungvari Z, Tarantini S, Kiss T ...
    ... mice. Am J Physiol Heart Circ Physiol 2014; 307: H1754-H1763 [PMID: 25326534 DOI: 10.1152/ajpheart ...
    O Criador:
    Kacena, M.A., Karnik, S., Li, J., Promer, H.J., Clauss, M., Loghmani, M.T., Wagner, D.R., McKinley, T.O., Nielsen, J.J., Low, P.S., Lowery, Jonathan W., Gunderson, Z.J., and Fennimore, A.
    Descrição:
    Successful fracture healing requires the simultaneous regeneration of both the bone and vasculature; mesenchymal stem cells (MSCs) are directed to replace the bone tissue, while endothelial progenitor cells (EPCs) form the new...
    Tipo:
    Article

  • Skeletal muscle mitochondrial dysfunction and muscle and whole body functional deficits in cancer patients with weight loss

    O Criador:
    Kaufman, K., Hart, C., Kumar, R., Jatoi, A., Gries, Kevin J., Port, J., Kunz, H., and Lanza, I.
    Descrição:
    Reductions in skeletal muscle mass and function are often reported in patients with cancer-associated weight loss and are associated with reduced quality of life, impaired treatment tolerance, and increased mortality. Although...
    Tipo:
    Article

  • Abnormal Trafficking of Endogenously Expressed BMPR2 Mutant Allelic Products in Patients with Heritable Pulmonary Arterial Hypertension

    Correspondências de palavras-chave:
    ... hypertension in heterozygous BMPR2-mutant mice. Am J Physiol Heart Circ Physiol 295: H677-H690. doi:10.1152 ...
    ... Cell Mol Physiol 287: L1241-L1247. doi:10.1152/ajplung. 00239.2004. PubMed: 15286002. 13. Burton VJ ...
    ... hypertension. Am J Physiol Regul Integr Comp Physiol 298: R833R842. doi:10.1152/ajpregu.00534.2009. PubMed ...
    ... Physiol 299: R1463-R1477. doi:10.1152/ajpregu.00866.2009. PubMed: 20881097. 32. West J, Cogan J, Geraci M ...
    ... Allelic Products in Patients with Heritable Pulmonary Arterial Hypertension. PLoS ONE 8(11): e80319. doi ...
    O Criador:
    Frump, A.L., Hamid, R., de Caestecker, M., Austin, E.D., and Lowery, Jonathan W.
    Descrição:
    More than 200 heterozygous mutations in the type 2 BMP receptor gene, BMPR2, have been identified in patients with Heritable Pulmonary Arterial Hypertension (HPAH). More severe clinical outcomes occur in patients with BMPR2...
    Tipo:
    Article

  • Obstructive Sleep Apnea Detection During Wakefulness: A Comprehensive Methodological Review

    Correspondências de palavras-chave:
    ... Physiol 105:13891405. https://doi.org/10.1152/JAPPLPHYSIOL. 90408.2008 Malhotra A, Pillar G, Fogel R et al ...
    ... 2005. Sleep 28:499523. https://doi. org/10.1093/SLEEP/28.4.499 3. American Academy of Sleep Medicine ...
    ... Respir J 22:167170. https://doi. org/10.1155/2015/516580 15. Yadollahi A, Moussavi Z (2009) Acoustic ...
    ... Physiol 99:24402450. https://doi.org/10. 1152/JAPPLPHYSIOL.00772.2005 Betts JG, DeSaix P, Johnson E et al ...
    ... sounds. Ann Biomed Eng. https://doi. org/10.1007/s10439-016-1720-5 Riley R, Guilleminault C, Herran J ...
    O Criador:
    Alqudah, A., Elwali, Ahmed, Kupiak, B., Hajipour, F., Jacobson, N., and Moussavi, Z.
    Descrição:
    Obstructive sleep apnea (OSA) is a chronic condition affecting up to 1 billion people, globally. Despite this spread, OSA is still thought to be underdiagnosed. Lack of diagnosis is largely attributed to the high cost,...
    Tipo:
    Article

  • Segregating the effects of ferric citrate-mediated iron utilization and FGF23 in a mouse model of CKD

    Correspondências de palavras-chave:
    ... Received: 12 November 2021 DOI: 10.14814/phy2.15307 | Accepted: 3 May 2022 ORIGINAL ARTICLE ...
    ... rescues renal anemia. The FASEB Journal, 32, 37523764. https://doi. org/10.1096/fj.201700667R Agoro, R ...
    ... regulation: Implications for the Anemia of CKD. American Journal of Kidney Diseases, 55, 726741. https://doi ...
    ... of Physiology, 470, 15691582. https://doi. org/10.1007/s00424-018-2171-7 Diehl, K. H., Hull, R ...
    ... ://doi. org/10.1677/JOE-10-0181 Farrow, E. G., Yu, X., Summers, L. J., Davis, S. I., Fleet, J. C., Allen ...
    O Criador:
    Liesen, Michael P., Agoro, R., Swallow, E., Noonan, M., Ni, P., Damrath, J., Wallace, J., Clinkenbeard, E., Allen, M., White, K. , and Hum, Julia
    Descrição:
    Ferric citrate (FC) is an approved therapy for chronic kidney disease (CKD) pa- tients as a phosphate (Pi) binder for dialysis-dependent CKD, and for iron de- ficiency anemia (IDA) in non-dialysis CKD. Elevated Pi and IDA...
    Tipo:
    Article

  • COVID-19 and the PAH patient: A retrospective chart review

    Correspondências de palavras-chave:
    ... ), European Heart Journal, 37(1), 67119. https://doi-org.forward.marian.edu/10.1093/eurheartj/ehv317 Hu, Y ...
    ... . Implementation Science: IS, 3, 1. https://doi-org.forward.marian.edu/10.1186/1748-5908-3-1 Klinger, J. R ...
    ... Physiology. Lung Cellular and Molecular Physiology, 319(2), L277L288. https://doi.org/10.1152/ajplung ...
    O Criador:
    Schmit, Ann
    Descrição:
    The COVID-19 pandemic has highlighted the need for additional health precautions in medically fragile populations. COVID-19 is a respiratory virus demonstrating increased mortality in individuals with risk factors such as...
    Tipo:
    Research Paper

  • Adipose tissue macrophage populations and inflammation are associated with systemic inflammation and insulin resistance in obesity

    O Criador:
    Hart, C, Gries, Kevin, Ryan, Z, Kunz, H, Laurenti, M, Polley, E, Zhang, X, Dalla Man, C, Moore, N, Lanza, I, Vella, A, Parvizi, M, and Jensen, M
    Descrição:
    Obesity is accompanied by numerous systemic and tissue-specific derangements, including systemic inflammation, insulin resistance, and mitochondrial abnormalities in skeletal muscle. Despite growing recognition that adipose...
    Tipo:
    Article