... , which upon addition to the W-20-17 cells resulted in a decrease in phosphorylation of SMAD 1/5/8 and no ...
... , which upon addition to the W-20-17 cells resulted in an increase in the phosphorylation of SMAD 1/5/8 ...
... ) pathway promotes bone formation through action of the effectors SMAD1/5/8 while the Activin pathway ...
... osteogenic cell line W-20-17. We first confirmed that W-20-17 cells respond to exogenous stimulation by BMP2 ...
... between these pathways. This revealed that, under basal conditions, SMAD1/5/8 activation is repressed by ...