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New Search Identifier Tesim https://doi.org/10.1038/s41598-018-23168-x

  • Identification of p38 MAPK as a Novel Therapeutic Target for Friedreich’s Ataxia

    Keyword matches:
    ... Information Supplementary information accompanies this paper at https://doi.org/10.1038/s41598-018-23168-x ...
    ... @mail.med.upenn.edu) SCIENTIFIC Reports | (2018) 8:5007 | DOI:10.1038/s41598-018-23168-x 1 www.nature.com ...
    ... :10.1038/s41598-018-23168-x 2 www.nature.com/scientificreports/ Figure 2. Partial loss of phenotype in ...
    ... | (2018) 8:5007 | DOI:10.1038/s41598-018-23168-x 3 www.nature.com/scientificreports/ Figure 3 ...
    ... Reports | (2018) 8:5007 | DOI:10.1038/s41598-018-23168-x 4 www.nature.com/scientificreports/ Figure 4 ...
    Creator:
    Lin, Daniel, Tobias, John W., Cotticelli, M. Gracia, Ruff, Eric, Wang, Yongping, Xia, Shujuan, Wilson, Robert B., and Kaur, Avinash
    Description:
    Friedreich ataxia (FRDA) is an autosomal recessive neuro- and cardio-degenerative disorder caused by decreased expression of frataxin, a protein that localizes to mitochondria and is critical for iron-sulfur-cluster (ISC)...
    Type:
    Article

  • Identification of p38 MAPK as a novel therapeutic target for Friedreich's ataxia

    Keyword matches:
    ... Information Supplementary information accompanies this paper at https://doi.org/10.1038/s41598-018-23168-x ...
    ... @mail.med.upenn.edu) SCIENTIFIC Reports | (2018) 8:5007 | DOI:10.1038/s41598-018-23168-x 1 www.nature.com ...
    ... :10.1038/s41598-018-23168-x 2 www.nature.com/scientificreports/ Figure 2. Partial loss of phenotype in ...
    ... | (2018) 8:5007 | DOI:10.1038/s41598-018-23168-x 3 www.nature.com/scientificreports/ Figure 3 ...
    ... Reports | (2018) 8:5007 | DOI:10.1038/s41598-018-23168-x 4 www.nature.com/scientificreports/ Figure 4 ...
    Creator:
    Kaur, Avinash , Wilson, Robert B., Wang, Yongping , Xia, Shujuan , Ruff, Eric , Cotticelli, M Grazia , Tobias, John W. , and Lin, Daniel
    Description:
    Friedreich ataxia (FRDA) is an autosomal recessive neuro- and cardio-degenerative disorder caused by decreased expression of frataxin, a protein that localizes to mitochondria and is critical for iron-sulfur-cluster (ISC)...
    Type:
    Article

  • Endothelial RhoA GTPase is essential for in vitro endothelial functions but dispensable for physiological in vivo angiogenesis.

    Keyword matches:
    ... angiogenesis in vitro. Sci Rep 8, 10495, https://doi.org/10.1038/s41598-018-28872-2 (2018). 75. Kokolakis, G ...
    ... : constantinos.mikelis@ttuhsc.edu) Scientific Reports | (2019) 9:11666 | https://doi.org/10.1038/s41598-019-48053-z 1 ...
    ... the VE-cadherin Scientific Reports | (2019) 9:11666 | https://doi.org/10.1038/s41598-019-48053-z 4 ...
    ... | (2019) 9:11666 | https://doi.org/10.1038/s41598-019-48053-z 5 www.nature.com/scientificreports ...
    ... and female mice. Scientific Reports | (2019) 9:11666 | https://doi.org/10.1038/s41598-019-48053-z 6 ...
    Creator:
    Tuz Zahra, Fatema, Kubota, Yoshiaki, Doci, Colleen L., Minchew, Shelby A., Cobos, Christopher, Gutkind, J. Silvio, Mikelis, Constantinos M., Zheng, Yi, Ichiyama, Yusuke, Sajib, Sanaullah, Tullar, Paul E., and Akwii, Racheal Grace
    Description:
    Imbalanced angiogenesis is a characteristic of several diseases. Rho GTPases regulate multiple cellular processes, such as cytoskeletal rearrangement, cell movement, microtubule dynamics, signal transduction and gene...
    Type:
    Article

  • A chromosome-scale genome sequence of sudangrass (Sorghum sudanense) highlights the genome evolution and regulation of dhurrin biosynthesis

    Keyword matches:
    ... . https://doi.org/10.1038/s41467-018-07271-1 17. Edgar RC, Myers EW (2005) PILER: identification and ...
    ... comparison for large-scale genomic experiments. Sci Rep 9:10274. https://doi.org/10.1038/s41598-019-46773-w ...
    ... of cultivated and wild sorghum. Nat Plants 7:766773. https://doi.org/10.1038/s41477-021-00925-x 48 ...
    ... . https://doi.org/10.1038/s41467-020-20236-7 11. Choi SC, Chung YS, Lee YG et al (2020) Prediction of ...
    ... metabolism. BMC Genomics 20:420. https://doi.org/10.1186/s12864-019-5734-x 14. Darbani B, Motawia MS, Olsen ...
    Creator:
    Bible, Paul, W., Wang, L., Jin, P., Zheng, J., Wang, Y., Zhan, Q., Li, J., Liu, Y., and Tu, W.
    Description:
    Sudangrass [ Sorghum sudanense (Piper) Stapf] is a hybrid between grain sorghum and its wild relative S. bicolor ssp. verticilliflorum and is grown as a forage crop due to its high biomass production and low dhurrin content...
    Type:
    Article

  • Temporal Transcriptomics of Gut Escherichia coli in Caenorhabditis elegans Models of Aging

    Keyword matches:
    ... . elegans. Sci Rep 7:7137. https://doi.org/10.1038/ s41598-017-07222-8. 16. Breton J, Tennoune N, Lucas N ...
    ... Caenorhabditis elegans. Sci Rep 9:5545. https://doi.org/10.1038/s41598-019-41452-2. 48. Pradel E, Zhang Y, Pujol ...
    ... metatranscriptomes. Nat Methods 15: 962968. https://doi.org/10.1038/s41592-018-0176-y. 64. Suzek BE, Wang Y, Huang H ...
    ... . https://doi.org/10.1038/ncb1975. 15. Smolentseva O, Gusarov I, Gautier L, Shamovsky I, DeFrancesco AS ...
    ... mutant that lives twice as long as wild type. Nature 366:461464. https:// doi.org/10.1038/366461a0 ...
    Creator:
    Brycky, J, Brislawn, C, Chan, Jason, Heibeck, N, Letson, G, Buonaccorsi, V, Unverdorben, L, Emlet, C, Chen See, J, and Lamendella, R
    Type:
    Article

  • The lipidomes of C. elegans with mutations in asm-3/acid sphingomyelinase and hyl-2/ceramide synthase show distinct lipid profiles during aging

    Keyword matches:
    ... . Sci Rep. 2017; 7:5. https://doi.org/10.1038/s41598-017-00037-7 PMID:28127055 12. Almeida I, Magalhes S ...
    ... elegans stress response. Nat Commun. 2018; 9:5152. https://doi.org/10.1038/s41467-018-07640-w PMID ...
    ... Spectrometry-based Metabolomics Data. Sci Rep. 2018; 8:663. https://doi.org/10.1038/s41598-017-19120-0 PMID ...
    ... :3346. https://doi.org/10.1038/srep03346 PMID:24284984 Jov M, Mota-Martorell N, Pradas I, Galo-Licona JD ...
    ... Sci. 2017; 42:81223. https://doi.org/10.1016/j.tibs.2017.07.001 PMID:28802547 18. Li X, Handee W, Kuo ...
    Creator:
    Staab, Trisha, McIntyre, Grace, Bromley, S., Raftery, D., Chan, Jason, Wang, L., Radeny, J., Bettcher, L., Guillen, Melissa, Peck, M. , and Kalil, A.
    Description:
    Lipid metabolism affects cell and physiological functions that mediate animal healthspan and lifespan. Lipidomics approaches in model organisms have allowed us to better understand changes in lipid composition related to age...
    Type:
    Research Paper

  • Segregating the effects of ferric citrate-mediated iron utilization and FGF23 in a mouse model of CKD

    Keyword matches:
    ... , 7294. https://doi.org/10.1038/ s41598-018-25439-z Nickolas, T. L., Stein, E. M., Dworakowski, E ...
    ... , 734744. https://doi.org/10.1681/ ASN.V133734 Francis, C., Courbon, G., Gerber, C., Neuburg, S., Wang, X ...
    ... , 345348. https://doi.org/10.1038/81664 Wolf, M., Koch, T. A., & Bregman, D. B. (2013). Effects of iron ...
    ... inflammation. Nephrology, Dialysis, Transplantation, 32, 960968. https://doi.org/10.1093/ndt/gfw376 Block, G. A ...
    ... Society of Nephrology, 30(8), 1495 1504. https://doi.org/10.1681/ASN.2018101016 Block, G. A., Fishbane, S ...
    Creator:
    Liesen, Michael P., Agoro, R., Swallow, E., Noonan, M., Ni, P., Damrath, J., Wallace, J., Clinkenbeard, E., Allen, M., White, K. , and Hum, Julia
    Description:
    Ferric citrate (FC) is an approved therapy for chronic kidney disease (CKD) pa- tients as a phosphate (Pi) binder for dialysis-dependent CKD, and for iron de- ficiency anemia (IDA) in non-dialysis CKD. Elevated Pi and IDA...
    Type:
    Article

  • Molecular Characterization of Bacterial Community Composition in the Rhizosphere of Invasive Plant Species Amur Honeysuckle (Lonicera Maackii) in an Urban Wetland Forest

    Keyword matches:
    ... Plant Growth. Scientific Reports, 9, Article No. 12832. https://doi.org/10.1038/s41598-019-49216-8 [45 ...
    ... Rarity and Invasiveness in Communities. Nature, 417, 67-70. https://doi.org/10.1038/417067a [3] Bever ...
    ... , 731-733. https://doi.org/10.1038/nature02322 [9] Shively, J.M., Samuel English, R., Baker, S.H. and ...
    ... . https://doi.org/10.1104/pp.110.155523 [16] Zhang, Q., Yang, R., Tang, J., Yang, H., Hu, S. and Chen, X ...
    ... Response Capacities. Nature Communications, 7, Article ID: 12485. https://doi.org/10.1038/ncomms12485 [23 ...
    Creator:
    Ahmad, Azeem and Akbar, Samina
    Description:
    The goal of this research was to determine the effects of the growth of invasive plant Amur Honeysuckle (Lonicera maackii) on the rhizosphere bacterial community composition, and diversity in an urban wetland forest ecosystem....
    Type:
    Article

  • Population differences in multimodal lizard communication are not well explained by habitat or history

    Keyword matches:
    ... ), 655662. https:// doi.org/10.1007/s00265-0 06-0209-x Bloch, N., & Irschick, D. J. (2006). An analysis of ...
    ... radiation. Nature Communications, 11(1), 4970. https://doi.org/10.1038/s41467-020-18772-3 Gunderson, A. R ...
    ... )? BMC Evolutionary Biology, 16(1), 63. https:// doi.org/10.1186/s12862-016-0628-x Leach, A. D., & Reeder ...
    ... Sociobiology, 72(12), 189. https://doi.org/10.1007/s00265-018-2617-0 Martins, E. P., Ossip-Klein, A. G., Zuniga ...
    ... cyclic dipeptides in a terrestrial vertebrate. Scientific Reports, 10(1), 4303. https://doi.org/10.1038 ...
    Creator:
    Romero-Diaz, C., Wetherell, B., Ury, D., Reuter, M., Pruett, J., Martins, E., and Ossip-Drahos, Alison G.
    Description:
    Animals evolve in complex selective regimes, where a suite of different factors can shape signal use. We might predict that more closely related species will exhibit more similar behavior than those more distantly related;...
    Type:
    Article

  • Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs

    Keyword matches:
    ... Article https://doi.org/10.1038/s41467-023-43012-9 Conserved chromatin and repetitive patterns ...
    ... expansion of satellites in the Nature Communications | (2024)15:579 https://doi.org/10.1038/s41467-023-43012 ...
    ... )15:579 https://doi.org/10.1038/s41467-023-43012-9 completeness in the other species. For analyses of ...
    ... and 4,661,928 3 Article https://doi.org/10.1038/s41467-023-43012-9 2n = 26 2n = 26 2n = 22 2n = 26 2n ...
    ... (i.e., .) represent translocation breakpoints. 5 Article https://doi.org/10.1038/s41467-023-43012-9 a ...
    Creator:
    Dredeson, J., Mudd, A., Hanken, J., Kerdivel, G., Medina-Ruiz, S., Buisine, N., Sachs, L., Buchholz, D., Kwon, T., Smith-Parker, H., Gridi-Papp, M., Ryan, M., Plott, C., Denton, Robert D., Malone, J., Wallingford, J., Mitros, T., Straight, A., Heald, R., Hockemeyer, D., Harland, R. , Rokhsar, D., Smith, O., Grimwood, J., Miller, K., Lyons, J, Batra, S., Park, J., Berkoff, K., Schmutz, J., Aguierre-Figueroa, G., Khokha, M., Lane, M., Philipp,I., and Laslo, M
    Description:
    Frogs are an ecologically diverse and phylogenetically ancient group of anuran amphibians that include important vertebrate cell and developmental model systems, notably the genus Xenopus. Here we report a high-quality...
    Type:
    Article