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New Search Date Created Tesim 4/1/2017

  • ABT-510 is an effective chemopreventive agent in the mouse 4-nitroquinoline 1-oxide model of oral carcinogenesis.

    Keyword matches:
    ... Research ABT-510 Is an Effective Chemopreventive Agent in the Mouse 4-Nitroquinoline 1-Oxide Model of Oral ...
    ... with preventive strategies. Using the 4-nitroquinoline 1-oxide (4-NQO) mouse model, we sought to define ...
    ... progression in an animal model whose genome is most similar to humans (1922). Although the 4-nitroquinoline 1 ...
    ... in mice with 4-nitroquinolone-1-oxide. Oral Surg Oral Med Oral Pathol 1984;57:52431. 13. Hawkins BL ...
    ... . Harvey ras (H-ras) point mutations are induced by 4-nitroquinoline-1-oxide in murine oral squamous ...
    Creator:
    Martin, Leslie E., Jones, Colleen L., Hasina, Rifat, Jalil, Asif, Lingen, Mark W., and Kasza, Kristen
    Description:
    Despite numerous advances, the 5-year survival rate for head and neck squamous cell cancer (HNSCC) has remained largely unchanged. This poor outcome is due to several variables, including the development of multiple primary...
    Type:
    Article

  • Mitigation of stomach dehiscence risk during gastrostomy tube changes - a retrospective analysis of patient outcomes.

    Creator:
    Smith, David A and Blocher-Smith, Ethan Charles OMS III
    Description:
    INTRODUCTION: Stomach dehiscence from the abdominal wall is a serious and potentially life-threatening complication of gastrostomy tube changes. This retrospective study evaluates gastric aspiration as an inexpensive and safe...
    Type:
    Conference Proceeding

  • Faculty Con 2017

    User Collection
    Faculty Con 2017 thumbnail
    Description:
    Faculty Con is an event designed to to inspire and support teaching excellence, encourage collaboration, and promote professional growth among the faculty at Marian University. The day includes keynote presentations and...
    0Collections
    6Works

  • Bmp2 and Bmp4 Exert Opposing Effects in Hypoxic Pulmonary Hypertension

    Creator:
    Jones, M.T., Frank, D.B., Mortlock, D.P., de Caestecker, M., Chandler, R.L., Anderson, L.A., and Lowery, Jonathan W.
    Description:
    The bone morphogenetic protein (BMP) type 2 receptor ligand, Bmp2, is upregulated in the peripheral pulmonary vasculature during hypoxia-induced pulmonary hypertension (PH). This contrasts with the expression of Bmp4, which is...
    Type:
    Article

  • The Fioretti (Spring 2017)

    Creator:
    Marian University - Indianapolis
    Type:
    Journal

  • Loss of the Nutrient Sensor Tas1R3 Leads to Reduced Bone Resorption

    Creator:
    Eaton, Michael and Newby, Jordan
    Description:
    Background: The Taste receptor, type 1 (TAS1R) family of heterotrimeric G protein-coupled receptors participates in monitoring energy and nutrient needs. TAS1R member 3 (TAS1R3) either recognizes amino acids such as glycine and...
    Type:
    poster

  • Loss of the Nutrient Sensor Tas1R3 Leads to Reduced Bone Resorption

    Creator:
    Ward, Taylor
    Description:
    The taste receptor type 1 (TAS1R) family of heterotrimeric G protein-coupled receptors participates in monitoring energy and nutrient status. TAS1R member 3 (TAS1R3) is a bi-functional protein that recognizes amino acids such...
    Type:
    poster

  • Bone Morphogenetic Protein-Based Therapeutic Approaches.

    Keyword matches:
    ... , 2017 - Published by Cold Spring Harbor Laboratory Press J.W. Lowery and V. Rosen Table 1. Components of ...
    ... , BDA-2A) BMP-4 (BMP-2B, BMP-2B1, MCOPS6, OFC11, ZYME) BMP-5 BMP-6 (VGR, VGR1) BMP-7 (OP-1) BMP-8A BMP ...
    ... Downloaded from http://cshperspectives.cshlp.org/ on April 10, 2017 - Published by Cold Spring ...
    ... Vicki Rosen2 1 Division of Biomedical Science, Marian University College of Osteopathic Medicine ...
    ... -1 and BMP-3, are not signaling molecules in the classical sense; BMP-1 is a metalloprotease that ...
    Creator:
    Rosen, Vicki and Lowery, Jonathan W.
    Description:
    Bone morphogenetic proteins (BMPs) constitute the largest subdivision of the transforming growth factor (TGF)-? family of ligands and exert most of their effects through the canonical effectors Smad1, 5, and 8. Appropriate...
    Type:
    Article

  • The Transcriptional Co-Repressor TLE3 Regulates Myogenic Differentiation by Repressing the Activity of the MyoD Transcription Factor

    Keyword matches:
    ... , 2017 Figure 1. TLE3 is expressed in activated and proliferating satellite cells of skeletal muscles. A ...
    ... November 13, 2017 Figure 4. TLE3 suppresses myoblast differentiation in C3H10T1/2 cells. A, whole-cell ...
    ... immunoprecipitated for 1 h at 4 C using anti-DDDDK (FLAG) tag mAb magnetic agarose (MBL) and anti-MyoD antibodies ...
    ... 3 ** 4 TLE3 0 Moc 2 Myf5 5 MCK0.8-luc 3 2 ** 1 Myogenin TLE3 MRF4 F 1.6 MCK0.8-luc 1.4 4 0 Moc 1 ...
    ... ** 1.2 1 0.8 0.6 0.4 0.2 0 Moc 6 ** 2 Moc 8 3 0 Relative expression 10 E Moc 12 4 Myogenin Relative ...
    Creator:
    Addison, William N, Yoda, Tetsuya, Rosen, Vicki, Nakatomi, Mitsushiro, Nakatomi, Chihiro, Urata, Mariko, Hitomi, Suzuro, Osawa, Kenji;, Jimi, Eijiro, Sato, Tsuyoshi, Ono, Yusuke, Kokabu, Shoichiro, Matsubara, Takuma, Hudnall, Aaron M, and Lowery, Jonathan W.
    Description:
    Satellite cells are skeletal muscle stem cells that provide myonuclei for postnatal muscle growth, maintenance, and repair/regeneration in adults. Normally, satellite cells are mitotically quiescent, but they are activated in...
    Type:
    Article

  • Investigating the HSF1-HSF2 Interaction

    Creator:
    Jaeger, Alex, Thiele, Dennis, and Wacker, Bryan
    Description:
    The over accumulation of misfolded protein aggregates is a key contributor in neurodegeneration associated with diseases such as Alzheimer’s, Parkinson’s, Huntington’s disease, and Amyotrophic Lateral Sclerosis (ALS). In a...
    Type:
    poster