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New Search Date Created Tesim 3/1/2010

  • The novel tumor suppressor NOL7 post-transcriptionally regulates thrombospondin-1 expression.

    Keyword matches:
    ... TSP-1 CL Doci et al 4380 Figure 3. NOL7 interacts with 30 end-processing proteins. (a) Lysate from ...
    ... thrombospondin-1 expression CL Doci, G Zhou and MW Lingen Thrombospondin-1 (TSP-1) is an endogenous inhibitor of ...
    ... angiogenesis whose expression suppresses tumor growth in vivo. Like many angiogenesis-related genes, TSP-1 ...
    ... an antiangiogenic phenotype and suppresses tumor growth, in part through upregulation of TSP-1. Here ...
    ... machinery and specically interacts with TSP-1 mRNA through its 30 UTR. Reintroduction of NOL7 into SiHa ...
    Creator:
    Zhou, G., Doci, Colleen L., and Lingen, M.W.
    Description:
    Thrombospondin-1 (TSP-1) is an endogenous inhibitor of angiogenesis whose expression suppresses tumor growth in vivo. Like many angiogenesis-related genes, TSP-1 expression is tightly controlled by various mechanisms, but there...
    Type:
    Article

  • Bmp2 and Bmp4 Exert Opposing Effects in Hypoxic Pulmonary Hypertension

    Creator:
    Jones, M.T., Frank, D.B., Mortlock, D.P., de Caestecker, M., Chandler, R.L., Anderson, L.A., and Lowery, Jonathan W.
    Description:
    The bone morphogenetic protein (BMP) type 2 receptor ligand, Bmp2, is upregulated in the peripheral pulmonary vasculature during hypoxia-induced pulmonary hypertension (PH). This contrasts with the expression of Bmp4, which is...
    Type:
    Article

  • The Fioretti (Spring 2010)

    Keyword matches:
    ... Spring 2010 EDITORS: Karen McNulty Aaron Wilder Charles Pefialosa EDITORS' NOTE: The word Fioretti ...
    ... Roach ................................ 19 3 PEOPLE SIFfING by Abigail Roach ...
    ... horizons and see where I end up. 15 ICE-BREAKERS By JONATHON CIANI 1. I plucked the Pleiades from their ...
    ... underwater in Atlantis and came back to tell you. Aren't you interested? 3. I've started a goat ranch in ...
    ... you. And how could you? It's 1:04 in the morning and I'm still wondering whyWhat is that you need? Why ...
    Creator:
    Marian University
    Type:
    Book

  • The Effect that Docosahexaenoic Omega-3 Fatty Acid Has on Intestinal Microbiome and its Relationship to Age-Related Macular Degeneration

    Creator:
    Mathias, Sydney, Willoughby, Macy, and Nunez, Andrea
    Type:
    Poster

  • Move, Adapt, or Die: Lagopus Leucura Changes in Distribution, Habitat and Number at Glacier National Park, Montana

    Keyword matches:
    ... Average Flock 5.0 5.1 3.0 5.0 4 flocks; 33 birds 2 flocks; 12 birds 3 flocks; 7 birds 1 flock; 11 birds ...
    ... Ptarmigan distribution, habitat, and numbers in 2009-2010 for comparison with 1996-1997 data. Briefly, five ...
    ... on Logan Pass moved 335 m upslope between the 1990s and 2009 and 2010. Ptarmigan in 2009 and 2010 ...
    ... numbers in late summer. Received 1 March 2011, accepted 20 June 2011. BENSON, D., AND M. CUMMINS. 2011 ...
    ... (Figure 1). Figure 1. Distribution of perennial snow on 22 August 1995 (231,499 m2) versus 27 August 2005 ...
    Creator:
    Benson, David P. and Cummins, M.
    Description:
    ABSTRACT.—Because of the “montane island” effect and relative rates of climate change, alpine species may be particularly affected by changing climate. White-tailed Ptarmigan (Lagopus leucura) are adapted to life in the alpine...
    Type:
    Article

  • BMP Signaling in Vascular Development and Disease.

    Creator:
    Lowery, Jonathan W. and de Caestecker, M.
    Description:
    Genetic and functional studies indicate that common components of the bone morphogenetic protein (BMP) signaling pathway play critical roles in regulating vascular development in the embryo and in promoting vascular homeostasis...
    Type:
    Article

  • ID Family Protein Expression and Regulation in Hypoxic Pulmonary Hypertension

    Creator:
    Jones, M.T., Frump, A.L., diCarlo, G.E., Lowery, Jonathan W, Anderson, L.A., and de Caestecker, M.
    Description:
    Bone morphogenetic protein (BMP) signaling has been linked to the development of pulmonary hypertension (PH). Inhibitors of differentiation (ID) proteins (ID1-4) are a family of basic helix-loop-helix transcription factors that...
    Type:
    Article

  • Dual inhibition of vascular endothelial growth factor receptor and epidermal growth factor receptor is an effective chemopreventive strategy in the mouse 4-NQO model of oral carcinogenesis.

    Keyword matches:
    ... ZD6474 Total 1 6 17 24 18 4 3 25 19 10 20 49 Cancer Prev Res; 3(11) November 2010 Downloaded from ...
    ... mechanisms of acquired resistance in the chemopreventive setting. Cancer Prev Res; 3(11); 1493502. 2010 AACR ...
    ... effective chemopreventive agent in the 4-NQO model. 1494 Cancer Prev Res; 3(11) November 2010 Materials and ...
    ... treatment cohorts (Fig. 1). Of note, the OSCC that arose in the ZD6474 treatment group (n = 3) had a mean PI ...
    ... numbers indicate mean SD. 1496 Cancer Prev Res; 3(11) November 2010 Cancer Prevention Research Downloaded ...
    Creator:
    Mankame, Tanmayi P., Zhou, Guolin, Wroblewski, Kristen, Lingen, Mark W., Doci, Colleen L., and Hasina, Rifat
    Description:
    Despite recent therapeutic advances, several factors, including field cancerization, have limited improvements in long-term survival for oral squamous cell carcinoma (OSCC). Therefore, comprehensive treatment plans must include...
    Type:
    Article

  • Identification and functional analysis of NOL7 nuclear and nucleolar localization signals.

    Keyword matches:
    ... ://www.biomedcentral.com/1471-2121/11/74 Page 3 of 20 Figure 1 NOL7 requires cytosolic factors for efficient nuclear ...
    ... 2010 Published: 27 September 2010 References 1. Lung ML, Choi CV, Kong H, Yuen PW, Kwong D, Sham J, Wei ...
    ... Genet Cytogenet 1998, 103(1):52-58. 3. Mutirangura A, Tanunyutthawongese C, Pornthanakasem W ...
    ... distinct pathogenetic pathways. Blood 2002, 99(1):3-9. 10. Giagounidis AA, Hildebrandt B, Heinsch M ...
    ... estrogen and glucocorticoid receptors. Cell Regul 1990, 1(3):291-299. 38. El Alami M, Feller A, Pierard A ...
    Creator:
    Zhou, Guolin, Lingen, Mark W., and Doci, Colleen L.
    Description:
    BACKGROUND: NOL7 is a candidate tumor suppressor that localizes to a chromosomal region 6p23. This locus is frequently lost in a number of malignancies, and consistent loss of NOL7 through loss of heterozygosity and decreased...
    Type:
    Article

  • Comparative Genomics Identifies the Mouse BMP3 Promoter and an Upstream Evolutionary Conserved Region (ECR) in Mammals.

    Keyword matches:
    ... , Yang K (2010) BMP-3 promotes mesenchymal stem cell proliferation through the TGF-beta/activin signaling ...
    ... , Vaysse F, Romeas A, et al. (2007) Localization of STRO-1, BMP-2/-3/-7, BMP receptors and phosphorylated ...
    ... -3 and Osteogenic Protein-1 during murine tooth root morphogenesis and in other craniofacial ...
    ... : 172176. 52. Yao S, Prpic V, Pan F, Wise GE (2010) TNF-alpha upregulates expression of BMP-2 and BMP-3 ...
    ... : 1119. 56. Johnson KJ, Robbins AK, Wang Y, McCahan SM, Chacko JK, et al. (2010) Insulin-like 3 exposure ...
    Creator:
    LaVigne, AW, Kokabu, S, Lowery, Jonathan W., and Rosen, V.
    Description:
    The Bone Morphogenetic Protein (BMP) pathway is a multi-member signaling cascade whose basic components are found in all animals. One member, BMP3, which arose more recently in evolution and is found only in deuterostomes,...
    Type:
    Article