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  • Therapeutic Discovery for Friedreich Ataxia Using Random shRNA Selection

    Schöpfer:
    Kaur, Avinash, Cotticelli, M., and Xia, Shujuan
    Beschreibung:
    2 fold, either as a vector-expressed shRNA or as a transfected siRNA. We randomly mutagenized gFA2 to create a gFA2 variant sub-library. We screened this sub-library in primary FA fibroblasts and identified two gFA2 variants,...
    Ressourcentyp:
    poster

  • Comparison of Patient Tolerance of Photodynamic Therapy with Zone vs. Full Face Treatment

    Schöpfer:
    Crawford, Dr. Kevin and Aleshaki, Joseph
    Beschreibung:
    Background: Zone based photodynamic therapy (PDT) is a promising treatment option for actinic keratosis, superficial basal cell carcinoma, and in-situ squamous cell carcinoma. PDT has similar cure rates to 5-fluorouracil and...
    Ressourcentyp:
    poster

  • Loss of the Nutrient Sensor Tas1R3 Leads to Reduced Bone Resorption

    Schöpfer:
    Eaton, Michael and Newby, Jordan
    Beschreibung:
    Background: The Taste receptor, type 1 (TAS1R) family of heterotrimeric G protein-coupled receptors participates in monitoring energy and nutrient needs. TAS1R member 3 (TAS1R3) either recognizes amino acids such as glycine and...
    Ressourcentyp:
    poster

  • Construction and Validation of a Novel Pathway Ratio Reporter System (PARRES)

    Schöpfer:
    Ote, Satoshi, King, Tyler, Lowery, Jonathan, and Rosen, Vickie
    Beschreibung:
    The Transforming Growth Factor-beta (TGFβ) superfamily is a large group of signaling molecules whose members play conserved roles in embryo specification, organogenesis, and tissue homeostasis. Structural considerations...
    Ressourcentyp:
    poster

  • Coding DNA into Music: An Alternate Way of Analysis

    Schöpfer:
    Fesenmeier, Sam
    Beschreibung:
    In the study, we are analyzing the human genome in order to determine patterns that may tell something about how DNA functions. Patterns require an explanation: it is highly improbable that they are random occurrence. These...
    Ressourcentyp:
    poster

  • Utility of a Scoring Tool for Living Kidney Donor Volunteers

    Schöpfer:
    Lien, Savahanna, Wiley, Linda, Stepan, Rebecca, Voges, Margaret, Dunn, Ty, and Lecuyer-Koich, Anne
    Beschreibung:
    A comprehensive yet efficient evaluation of living kidney donor volunteers (LKDV) is key to a successful transplant program. Donor selection is complex and must balance donor medical suitability, compatibility issues and donor...
    Ressourcentyp:
    poster

  • Anti-Inflammatory and Anti-Angiogenic Effects of Black Raspberry Extract on Human Esophageal and Intestinal Microvascular Endothelial Cells

    Schöpfer:
    Schmidt, Jamie, Jovanovic, Nebojsa, Link, Benjamin, Rafiee, Parvaneh, Nie, Linghui, Otterson, Mary, Lyros, Orestis, Stoner, Gary, Medda, Rituparna, and Shaker, Reza
    Beschreibung:
    Polyphenolic compounds (anthocyanins, flavonoid glycosides) in berries prevent the initiation, promotion, and progression of carcinogenesis in rat’s digestive tract and esophagus, in part, via anti-inflammatory pathways....
    Ressourcentyp:
    poster

  • Characterization of Spatio-Temporal Expression of Novel Hypoxia-Induced Genes in Zebrafish

    Schöpfer:
    Amir, Adam and Imam, Farhad
    Beschreibung:
    Hypoxia is a critical stress that can affect the normal development of a mammal embryo. Normally, Hypoxia is buffered by the Utero-placental apparatus in human infants; however, prematurely delivered infants may encounter...
    Ressourcentyp:
    poster

  • Single-Center Denial Reasons for Potential Living Kidney Donors

    Schöpfer:
    Lien, Savahanna, Matas, Arthur, Voges, Margaret, and Garvey, Cathy
    Beschreibung:
    Because of the benefits of preemptive living donor (LD) transplant, the desire for LD is rising. However, in the last decade, there has been no increase in LD in the U.S, possibility due to older donor candidate population...
    Ressourcentyp:
    poster

  • Kidney Paired Donation: National Activity and Perspectives

    Schöpfer:
    Lien, Savahanna, Abt, Peter, Fayek, Sameh, Marsh, Christopher, and Dunn, Ty
    Beschreibung:
    While utilization of Kidney Paired Donation (KPD) continues to increase, the potential is not fully realized. We surveyed kidney transplant (KTX) professionals to evaluate perceptions of barriers and solutions to increasing KPD...
    Ressourcentyp:
    poster