Desrosiers, Megan, Ahmad, Azeem, Akbar, Samina, and Antolin, Bridgette
Beschreibung:
The spread of antibiotic resistance among bacteria is a potential threat to the effectiveness of antibiotics currently used for controlling common human pathogens. Also, the resistance to current antibiotics is spreading at a...
LaFontaine, Michael, Metzler-Wilson, Kristen, and Willcox, Kendal
Beschreibung:
Over the past twenty years, opioid drug use has increased, causing an epidemic of opioid abuse that is killing tens of thousands of people every year. Current treatment options for opioid abuse disorder include alternative...
Morscher, Melanie, Steiner, Richard, Weiner, Dennis, Adamczyk, Mark, Childs, Robin, Yang, Julianne, Bundy, Joshua, and Landis, William
Beschreibung:
Context: This research may provide insight into human articular cartilage development, repair mechanisms, and diseases such as arthritis. Objective: The purpose of this study is to compare the proximal femur articular cartilage...
Hickman, Susan, Unroe, Kathleen, Mobley, Meaghan, and Miller, Luke
Beschreibung:
CONTEXT. Prior research has shown that nursing home residents have a significant burden of symptoms including pain, nervous and depressed feelings, fatigue, and lack of energy. OPTIMISTIC is an 8-year initiative funded by the...
Hypertension is an established risk factor for the development of atrial fibrillation (AF). We evaluated the association and population impact of hypertension defined using the new 2017 guidelines on risk of AF. In this...
Mulye, Minal, Libbing, Cassandra, and Azcueta, Rea-Mae
Beschreibung:
Context: Lipid droplets (LDs) are cytoplasmic lipid storage organelles that have recently gained importance in host-pathogen interactions. Surrounded by a phospholipid monolayer, they store excess cellular free fatty acids and...
Context: Lipid droplets (LDs) are cytoplasmic lipid storage organelles that have recently gained importance in host-pathogen interactions. They are surrounded by a phospholipid monolayer and store excess cellular free fatty...
Coxiella burnetii is an obligate intracellular bacterial pathogen and causative agent of Q fever. Chronic Q-fever manifests as potentially fatal endocarditis weeks to years after initial infection, suggesting Coxiella’s ability...
Cudjoe, Lorene, Kato, Roberta, Coates, Thomas, and Shah, Payal
Beschreibung:
Context: Sickle Cell Disease (SCD) is characterized by an inherited point mutation in the hemoglobin (Hgb) HBB gene, which results in hemoglobin polymerization and red blood cell sickling when not fully oxygenated. Inflammatory...
Coxiella burnetii is a Gram-negative obligate intracellular pathogen, which spreads via inhalation. Although it initially infects alveolar macrophages, it can cause endocarditis several months to years after infection. This...