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The impact of C. elegans ceramide glucosyltransferase enzymes on the beneficial effects of B. subtilis lifespan

Creator:

Arvin, Chelsey L., Sibila, Zachary, Lamendella, R., Chan, Jason, and Staab, Trisha

Description:

Ceramide glucosyltransferase (CGT) adds sugar moieties to ceramide, forming glucosylceramides that play roles in immune signaling, stress response, and host-bacterial interactions. Here, we examined whether mutations in cgt...

Type:

Article
The functional loss of ceramide metabolism enzymes ceramide synthase and acid sphingomyelinase on lipid metabolism and healthspan

Creator:

Wang, Lou, Staab, Trisha, Radeny, J, McIntyre, Grace, and Chan, Jason

Description:

The increase in our aging population in combination with the growing incidence of late-life conditions presents a need for research on healthy aging. Here, we present work examining the roles of sphingolipid metabolism on...

Type:

Conference Proceeding