Recherche

Nouvelle recherche Créateur Thompson, William

  • Role of CaMKK2 in Mechanical Stimulation of Bone

    Créateur:
    Patel, Sheel, Bello, Margaret , Warrick, Adam , Sankar, Uma, Robling, Alexander , Thompson, William, Shutter, Jennifer , Bellido, Teresita , and Williams, Justin
    La description:
    There is a need for anabolic therapies to treat degenerative bone diseases. Mechanical loading stimulates anabolic and inhibits catabolic pathways of bone leading to increased bone formation. Osteocytes are the bone cell...
    Type:
    Poster

  • Mechanical stimulation in vitro regulates pro-inflammatory cytokines: potential insight into soft tissue manual therapies for osteopenia and sarcopenia

    Créateur:
    Larsen, Bryan, Ogunbekun, Oladipupo, Loghmani, M. Terry, Thompson, William, Hum, Julia, Hiland, Taylor, Lowery, Jonathan, Mahoney, Aaron, and Anloague, Aric
    La description:
    Objecti ve: Soft tissue manual therapies are commonly utilized by osteopathic physicians, chiropractors, physical therapists and massage therapists. These techniques are predicated on subjecting tissues to biophysical...
    Type:
    Poster

  • Bone-derived Sclerostin has endocrine actions in adipocyte precursors and pancreatic beta-cells

    Créateur:
    Nelson, Jessica, Ghazzawi, Ziad, Evans-Molina, Carmela, Thompson, William, Cregor, Meloney, Bellido, Teresita, Daniel, Ashley, Delgado-Calle, Jesus, Ferrari, Adam, Sabol, Hayley, and McAndrews, Kevin
    La description:
    Osteocyte (Ot)-derived Sclerostin (Scl) has local actions in bone mediated by Lrp 4/5/6 receptors, inhibiting bone formation and stimulating bone resorption by antagonizing Wnt signaling. Emerging evidence suggests that Scl...
    Type:
    poster

  • Osteocyte-Specific Deletion of the α2δ1 Auxiliary Voltage Sensitive Calcium Channel Subunit

    Créateur:
    Yi, Xin, Schneider, Artur, Wright, Christian, Hum, Julia, and Thompson, William
    La description:
    Context: Skeletal unloading due to disuse, disease, or aging increases bone loss and the risk of skeletal fracture. Conversely, mechanical loading is anabolic to the skeleton, promoting skeletal integrity through increased bone...
    Type:
    poster