Patel, Sheel, Bello, Margaret , Warrick, Adam , Sankar, Uma, Robling, Alexander , Thompson, William, Shutter, Jennifer , Bellido, Teresita , and Williams, Justin
Description:
There is a need for anabolic therapies to treat degenerative bone
diseases. Mechanical loading stimulates anabolic and inhibits
catabolic pathways of bone leading to increased bone formation.
Osteocytes are the bone cell...
Larsen, Bryan, Ogunbekun, Oladipupo, Loghmani, M. Terry, Thompson, William, Hum, Julia, Hiland, Taylor, Lowery, Jonathan, Mahoney, Aaron, and Anloague, Aric
Description:
Objecti ve: Soft tissue manual therapies are commonly utilized by osteopathic physicians, chiropractors, physical therapists and massage therapists. These techniques are predicated on subjecting tissues to biophysical...
Osteocyte (Ot)-derived Sclerostin (Scl) has local actions in bone mediated by Lrp 4/5/6 receptors, inhibiting bone formation and stimulating bone resorption by antagonizing Wnt signaling. Emerging evidence suggests that Scl...
Yi, Xin, Schneider, Artur, Wright, Christian, Hum, Julia, and Thompson, William
Description:
Context: Skeletal unloading due to disuse, disease, or aging increases bone loss and the risk of skeletal fracture. Conversely, mechanical loading is anabolic to the skeleton, promoting skeletal integrity through increased bone...