Recherche

Nouvelle recherche Créateur McAndrews, Kevin

  • Bone-derived Sclerostin has endocrine actions in adipocyte precursors and pancreatic beta-cells

    Créateur:
    Nelson, Jessica, Ghazzawi, Ziad, Evans-Molina, Carmela, Thompson, William, Cregor, Meloney, Bellido, Teresita, Daniel, Ashley, Delgado-Calle, Jesus, Ferrari, Adam, Sabol, Hayley, and McAndrews, Kevin
    La description:
    Osteocyte (Ot)-derived Sclerostin (Scl) has local actions in bone mediated by Lrp 4/5/6 receptors, inhibiting bone formation and stimulating bone resorption by antagonizing Wnt signaling. Emerging evidence suggests that Scl...
    Type:
    poster

  • Bone-derived Sclerostin Regulates Glucose Metabolism Via Endocrine Actions in Pancreatic β- cells

    Créateur:
    Nelson, Jessica, Evans-Molina, Carmella, Cregor, Meloney, Bellido, Teresita, Delgado-Calle, Jesus, Ferrari, Adam, and McAndrews, Kevin
    La description:
    Osteocyte (Ot)-derived Sclerostin (Scl), encoded by the SOST gene, regulates bone homeostasis by acting on osteoblasts, inhibiting bone formation and stimulating bone resorption. Emerging evidence suggest that Scl has...
    Type:
    poster