Busca

Nova pesquisa O Criador Lowery, Jonathan W.

  • An Integrated Approach to Clinical and Translational Metabolism Research

    O Criador:
    Lowery, Jonathan W.
    Descrição:
    Welcome to the first issue of the new Clinical & Translational Metabolism. It is my privilege and honor to serve as the editor-in-chief and establish this journal as an integrative venue for high-quality research from clinical...
    Tipo:
    Article

  • PTHrP intracrine actions divergently influence breast cancer growth through p27 and LIFR

    O Criador:
    Edwards, C., Kane, J., Johnson, J., Hernandez Diaz, M., Vecchi, L., Bracey, K., Omokehinde, T., Fontana, J., Karno, B., Scott, H. , Vogel, Carolina, J. , Lowery, Jonathan W., Martin, T., Johnson, R. , Smith, J., and Grant, D.
    Descrição:
    The role of parathyroid hormone (PTH)-related protein (PTHrP) in breast cancer remains controversial, with reports of PTHrP inhibiting or promoting primary tumor growth in preclinical studies. Here, we provide insight into...
    Tipo:
    Article

  • Editorial: Genetic and molecular determinants in bone health and diseases

    O Criador:
    Rossi, M., Lowery, Jonathan W., and Del Fattore, A.
    Descrição:
    Alterations of bone remodeling impact skeletal integrity lead to excessive or impaired bone resorption as well as reduced or disorganized bone formation (1, 2). This Research Topic focuses on the identification of genetic and...
    Tipo:
    Article

  • Soft Tissue Manipulation Alters RANTES/CCL5 and IL-4 Cytokine Levels in a Rat Model of Chronic Low Back Pain

    O Criador:
    Marciano, Carmela L., Hiland, Taylor A., Chu, TM, Kang, Kyung S., Lowery, Jonathan W., Jackson, Krista L., Street, Sierra, Maris, Carson, Ehrsam, Andrew, Hum, Julia M. , and Loghmani, M
    Descrição:
    Low back pain (LBP) is a common musculoskeletal complaint that can impede physical function and mobility. Current management often involves pain medication, but there is a need for non-pharmacological and non-invasive...
    Tipo:
    Article

  • Addressing Motivations and Barriers to Research Involvement during Medical School among Osteopathic Medical Students in the United States

    O Criador:
    Zahl, Sarah, Hum, Julia M., Jackson, Krista L., Griffin, Nicole, Lowery, Jonathan W., Nick, Benjamin, Herber, Jake, Hamby, T., Baumann, Michael, and Ogunbekun, Oladipupo
    Descrição:
    Involvement in research is regarded as a high-impact educational practice, which, for medical professionals, is associated with sharpened critical thinking and life-long learning skills, greater appreciation for evidence-based...
    Tipo:
    Article

  • Muscle-derived factors influencing bone metabolism

    O Criador:
    Zysik, Victoria S., Gries, Kevin, Jobe, Tyler K., Leeds, Benjamin P., Lowery, Jonathan W., and Griffin, Nicole
    Descrição:
    A significant amount of attention has been brought to the endocrine-like function of skeletal muscle on various tissues, particularly with bone. Several lines of investigation indicate that the physiology of both bone and...
    Tipo:
    Article

  • Identification of Commercially-Available Antibodies that Block Ligand-Binding by BMPR2

    O Criador:
    Hum, Julia M., Schoerning, Laura OMSII, Gorrell, Ruthann E., Newby, Jordan B., and Lowery, Jonathan W.
    Descrição:
    Osteoporosis, a disease of low bone mineral density, affects 10 million Americans and is a significant health problem and a considerable socioeconomic burden. Current treatments for osteoporosis have significant limitations,...
    Tipo:
    poster

  • Identification of a bone morphogenetic protein type 2 receptor neutralizing antibody

    O Criador:
    Newby, Jordan B., Hum, Julia M., Gorrell, Ruthann, Schoerning, Laura, Lowery, Jonathan W., Lawless, Warren, Totten, Madeline, and Geyman, Logan J.
    Descrição:
    The bone morphogenetic protein (BMP) signaling pathway comprises the largest subdivision of the transforming growth factor (TGF?) superfamily. BMP signaling plays essential roles in both embryonic development and postnatal...
    Tipo:
    Article

  • Comparison of Human Cytokine Array, Cytokine Bead Arrays, and Protein ELISA in determining cytokine production in media supernatant from in vitro strain of human dermal fibroblasts

    O Criador:
    Anloague, Aric and Lowery, Jonathan W.
    Descrição:
    This experiment analyzes three different techniques used in literature to detect cytokine release from cells in vitro: the Human Cytokine Array (HCA) by R&D Systems, the BD Cytometric Bead Array (CBA) assay, and protein...

  • Dysfunctional Stem and Progenitor Cells Impair Fracture Healing with Age

    O Criador:
    Kacena, M.A., Karnik, S., Li, J., Promer, H.J., Clauss, M., Loghmani, M.T., Wagner, D.R., McKinley, T.O., Nielsen, J.J., Low, P.S., Lowery, Jonathan W., Gunderson, Z.J., and Fennimore, A.
    Descrição:
    Successful fracture healing requires the simultaneous regeneration of both the bone and vasculature; mesenchymal stem cells (MSCs) are directed to replace the bone tissue, while endothelial progenitor cells (EPCs) form the new...
    Tipo:
    Article