Thompson, William R., Kelly, Madison, Bender, Cecelia, Hum, Julia, Oberhelman, Forrest, and Young, Collin
Description:
Voltage sensitive calcium channels (VSCCs) are key components in coordinating extracellular signaling that influence calcium (Ca2+) influx and subsequent downstream signaling in a variety of tissues including bone. Previous...
Shadmand, Mehdi, Lucas, Tyler, Kelly, Madison, Hum, Julia, and Sharma, Curren Robling, Alexander
Description:
Context: In states of health, bone mass is sustained in a coordinated effort by osteoblasts, osteoclasts, and osteocytes. WNT signaling through low-density lipoprotein receptor related protein 5/6 (LRP5/LRP6) is one of the...
Farach-Carson Mary, Sharma, Karan, Kelly, Madison, Hum, Julia, Noonan, Megan, Yi, Xin, and Robling, Alexander
Description:
Mechanical loading is critical for bone remodeling. Voltage sensitive calcium channels (VSCCs) influence bone development and responses to loading. The α<sub>2</sub>δ<sub>1</sub> VSCC subunit regulates osteocyte...