Ricerca

Nuova ricerca Creatore Eaton, Michael

  • Nutrient Sensing by Tas1R Proteins is Required for Normal Bone Resorption

    Creatore:
    Shively, Stephen, Davis, Hannah M, Weinstein, Nicholas, Eaton, Michael, Plotkin, Lillian, and Lowery, Jonathan
    Descrizione:
    Current therapies for low bone mass consist of inhibiting osteoclast activity or increasing the PTH or Wnt signaling pathways. These approaches have significant drawbacks that limit their use in specific patient populations...
    Tipo di risorsa:
    poster

  • Loss of BMPR2 Expression in Skeletal Progenitor Cells Reduces Age-Related Bone Loss

    Creatore:
    Eaton, Michael
    Descrizione:
    Osteoporosis is a disease of low bone mineral density that affects 10 million Americans and accounts for 1.5 million fractures annually. With an additional 34 million Americans at risk for developing the disease, osteoporosis...
    Tipo di risorsa:
    poster

  • Loss of BMPR2 Expression in Skeletal Progenitor Cells Reduces Age-Related Bone Loss

    Creatore:
    Rosen, Vickie, Hudnall, Aaron, Eaton, Michael, Newby, Jordan, and Lowery, Jonathan
    Descrizione:
    Osteoporosis is a disease of low bone mineral density (BMD) that affects 10 million Americans with an additional 34 million at risk for developing the disease. Current FDA-approved therapies for osteoporosis involve...
    Tipo di risorsa:
    poster

  • Loss of the Nutrient Sensor Tas1R3 Leads to Reduced Bone Resorption

    Creatore:
    Eaton, Michael and Newby, Jordan
    Descrizione:
    Background: The Taste receptor, type 1 (TAS1R) family of heterotrimeric G protein-coupled receptors participates in monitoring energy and nutrient needs. TAS1R member 3 (TAS1R3) either recognizes amino acids such as glycine and...
    Tipo di risorsa:
    poster