Shively, Stephen, Davis, Hannah M, Weinstein, Nicholas, Eaton, Michael, Plotkin, Lillian, and Lowery, Jonathan
Description:
Current therapies for low bone mass consist of inhibiting osteoclast activity or increasing the PTH or Wnt signaling pathways. These approaches have significant drawbacks that limit their use in specific patient populations...
Arthur, Jon, Shively, Stephen R, Wauson, Eric M, Shor, Ryann, Newby, Jordan B, Davis, Hannah M, Plattes, Maggie M, Eaton, Michael S., Weinstein, Nicholas, Nathan, Justin, Foster, Hanna E, Ward, Taylor D, Broege, Aaron, Lowery, Jonathan W. Ph.D., Plotkin, Lilian I, and Dewar, Brian J
Description:
The taste receptor type 1 (TAS1R) family of heterotrimeric G protein-coupled receptors participates in monitoring energy and nutrient status. TAS1R member 3 (TAS1R3) is a bi-functional protein that recognizes amino acids such...